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  • M.Sc. // Application of droplet microfluidics for field-resolved infrared spectroscopy

    The Field-Resolved Infrared Spectroscopy (FRIS) Group (www.attoworld.de/fris), located at the Chair of Experimental Physics of Prof. Ferenc Krausz at Ludwig-Maximilians-Universität München (LMU), together with the Max Planck Institute of Quantum Optics (MPQ) and the Center for Molecular Fingerprinting (CMF, www.cmf.hu) is pioneering ultrafast femtosecond laser technologies to advance field-resolved infrared spectroscopy for molecular fingerprinting.

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    In collaboration with the Molecular Biophysics Group of Dr. Georg Krainer (www.molecular-biophysics.uni-graz.at/en) at the University of Graz, an expert in microfluidics, we are working on integrating microfluidic systems with field-resolved infrared spectroscopy. The resulting microfluidics-integrated laser spectrometers hold strong potential for application in large-scale clinical studies for early disease detection (see www.lasers4life.de and www.h4h.hu), enabling high-throughput measurements of human samples coupled with clinical metadata.

    Project overview:

    We are seeking for highly motivated and skilled students to join our team. The project focuses on exploring the applicability of droplet microfluidics for handling small sample volumes to enhance field-resolved infrared spectroscopy measurements. This work has the potential to contribute to development of molecular fingerprinting techniques for clinical sample analysis, ultimately aiming to improve healthcare in the long term. Major tasks will include assembling and testing a system for reproduceable droplet generation (both single and double emulsions), assessing the impact of various surfactants and oils on spectral measurements with field-resolved infrared spectroscopy, integrating the droplet generation system with the laser-based field-resolved infrared spectroscopy setup, and conducting experiments to evaluate the potential of droplet microfluidics for advancing spectral measurements of small sample volumes.

    Required qualifications:

    1. BSc background in microfluidics, physics, automation, biology, chemistry or related fields;
    2. Enthusiasm to combine microfluidics and latest developments in laser physics to advance clinical diagnostics for better health care.

    Position Details:

    1. Location: Research Center Garching, Faculty of Physics at LMU, Am Coulombwall 1, 85748 Garching;
    2. Possibility for a research visit at the University of Graz.

    For application, please send the following documents to to Eszter Márton-Szűcs, as the HR associate:

    1. A brief cover letter explaining your interest in the position, and your qualification;
    2. Your CV;
    3. Your bachelor and master transcripts;
    4. Contact information for two references.

    Contact:
    Dr. Alexander Weigel
    Email: alexander.weigel@mpq.mpg.de
    Dr. Igor Kukhtevich
    Email: igor.kukhtevich@lmu.de
    Dr. Georg Krainer
    Email: georg.krainer@uni-graz.at

    If you are interested in this exciting opportunity to contribute to better health care, please send us your CV and study transcripts. Also, please write a couple of lines about your motivation.

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